After a strange encounter, Kyle ends up a vampire and, through a twist of fate, he finds himself in an unusual symbiotic relationship with Cartman. It's unsustainable, though, and Kyle is forced to accept the fact that he'll need to regularly kill to survive. Cartman has a plan, however, and the two of them form an unlikely duo and, together, they hunt down and kill deviants such as pedophiles, sexual predators, and neo-Nazis.